Global Solid Phase Extraction SPE Disk Market Insights, Size, and Forecast By Technique (Manual Solid Phase Extraction, Automated Solid Phase Extraction, Vacuum-Based Solid Phase Extraction, Pressure-Based Solid Phase Extraction), By Product Type (C18 Disks, C8 Disks, Strong Anion Exchange Disks, Strong Cation Exchange Disks, Mixed Mode Disks), By End Use (Laboratories, Research Institutions, Quality Control Facilities, Manufacturing Units), By Application (Pharmaceuticals, Environmental Testing, Food and Beverage, Chemical Analysis, Clinical Research), By Region (North America, Europe, Asia-Pacific, Latin America, Middle East and Africa), Key Companies, Competitive Analysis, Trends, and Projections for 2026-2035
Key Market Insights
Global Solid Phase Extraction SPE Disk Market is projected to grow from USD 0.38 Billion in 2025 to USD 0.75 Billion by 2035, reflecting a compound annual growth rate of 7.4% from 2026 through 2035. The Solid Phase Extraction SPE Disk market encompasses the global sales and distribution of SPE disks, which are essential sample preparation tools used to extract and concentrate analytes from complex matrices across various scientific disciplines. These disks offer advantages over traditional cartridge formats due to their higher flow rates and reduced clogging, making them ideal for high throughput applications. Key drivers propelling market growth include the escalating demand for accurate and sensitive analytical testing across industries such as pharmaceuticals, food safety, environmental monitoring, and clinical diagnostics. Furthermore, the increasing adoption of automated SPE systems, which often utilize disk formats, is contributing significantly to market expansion by enhancing efficiency and reproducibility. The market is segmented by Application, Product Type, End Use, and Technique, reflecting the diverse utility of these products.
Global Solid Phase Extraction SPE Disk Market Value (USD Billion) Analysis, 2025-2035
2025 - 2035
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A significant trend observed in the SPE disk market is the continuous innovation in sorbent chemistries, with manufacturers developing novel materials to improve selectivity and recovery for a wider range of analytes. This focus on advanced materials is crucial for addressing the evolving challenges in sample preparation. However, the market faces restraints such as the relatively high initial cost of automated SPE disk systems and the need for specialized expertise to optimize complex SPE methods. Despite these challenges, substantial opportunities exist in the development of greener SPE techniques that utilize fewer organic solvents, aligning with increasing environmental consciousness and regulatory pressures. Additionally, the expansion of research and development activities, particularly in emerging economies, presents a fertile ground for market penetration and growth. North America currently dominates the market, primarily due to the strong presence of established pharmaceutical and biotechnology companies, well-developed analytical infrastructure, and high investment in R&D.
Asia Pacific is anticipated to be the fastest-growing region, driven by rapid industrialization, increasing healthcare expenditure, and a burgeoning life sciences sector. This region is witnessing a surge in contract research organizations and analytical testing laboratories, fueling the demand for efficient sample preparation solutions. Among the product types, C18 Disks hold the largest market share, attributable to their versatility and wide applicability in reversed-phase extraction for a broad spectrum of compounds. Key players in this competitive landscape include PALL Corporation, Vici Dialysis, Biotage, Hichrom Limited, Agilent Technologies, Thermo Fisher Scientific, Merck KGaA, PerkinElmer, J.T. Baker, and SPEX SamplePrep. These companies are actively engaged in strategic initiatives such as product innovation, mergers and acquisitions, and geographic expansion to strengthen their market position and cater to the growing global demand for advanced SPE disk solutions. Their strategies are focused on enhancing product portfolios, improving customer service, and leveraging technological advancements to maintain a competitive edge.
Quick Stats
Market Size (2025):
USD 0.38 BillionProjected Market Size (2035):
USD 0.75 BillionLeading Segment:
C18 Disks (42.5% Share)Dominant Region (2025):
North America (38.2% Share)CAGR (2026-2035):
7.4%
What is Solid Phase Extraction SPE Disk?
A Solid Phase Extraction SPE Disk is a chromatographic tool used for sample preparation. It’s essentially a flat, circular membrane incorporating a sorbent material, like silica or polymers, which is bonded within a inert matrix. The disk facilitates the separation and concentration of target analytes from complex liquid samples by passing the sample through it. Chemical interactions between the analytes and the sorbent selectively retain the compounds of interest, while unwanted matrix components pass through. Subsequent elution with a suitable solvent recovers the purified analytes. This method is crucial for enhancing sensitivity and removing interferences in analytical techniques, finding wide application in environmental, pharmaceutical, and clinical analyses.
What are the Trends in Global Solid Phase Extraction SPE Disk Market
Automated SPE Disk Systems Ascend
Micro Extraction Disks Dominate
Bioanalytical Sample Prep Evolves
Sustainable SPE Solutions Emerge
Automated SPE Disk Systems Ascend
Automated SPE disk systems are gaining prominence due to their efficiency and reduced manual intervention. They offer high throughput, improved reproducibility, and enhanced accuracy in sample preparation. This shift minimizes human error and optimizes laboratory workflows, making them increasingly attractive for researchers and industries requiring reliable and standardized extraction methods, ultimately driving their accelerated adoption.
Micro Extraction Disks Dominate
Micro extraction disks are increasingly preferred due to their superior efficiency and enhanced analyte recovery in sample preparation. Their smaller size and innovative design optimize extraction processes, reducing solvent consumption and analysis time. This allows for more precise and rapid separations, making them the leading choice for laboratories globally seeking improved analytical workflows and higher throughput in solid phase extraction applications.
Bioanalytical Sample Prep Evolves
Bioanalytical sample prep is evolving. SPE disks are crucial for extracting analytes from complex biological matrices like plasma and urine. Automation and miniaturization are key. Faster, more efficient methods are demanded for drug discovery, diagnostics, and metabolomics. Disks offer cleaner samples, removing interferences and concentrating analytates, improving downstream analytical accuracy. This evolution drives demand for innovative disk chemistries and formats, optimizing recovery and reproducibility in diverse applications.
Sustainable SPE Solutions Emerge
Sustainable SPE solutions are gaining prominence in the global disk market. Manufacturers are developing greener products minimizing solvent use and waste generation. This shift emphasizes eco friendly materials and renewable resources throughout the SPE disk lifecycle. Companies prioritize reducing environmental impact while maintaining extraction efficiency. This trend reflects increasing industry demand for responsible and resource efficient analytical sample preparation methods.
What are the Key Drivers Shaping the Global Solid Phase Extraction SPE Disk Market
Increasing Demand in Pharmaceutical and Biotech R&D
Growing Adoption in Environmental Monitoring and Food Safety
Advancements in SPE Disk Technology and Automation
Rising Need for High-Throughput and Efficient Sample Preparation
Increasing Demand in Pharmaceutical and Biotech R&D
Rising research and development in pharmaceuticals and biotechnology fuels the need for efficient sample preparation. Drug discovery, development, and quality control processes increasingly rely on solid phase extraction disks for isolating and purifying target compounds from complex matrices. This growing scientific activity drives demand for SPE disk technology as researchers seek improved analytical accuracy, sensitivity, and throughput for their critical experiments.
Growing Adoption in Environmental Monitoring and Food Safety
Increased awareness of environmental pollution and foodborne illnesses drives demand for accurate contaminant detection. Solid Phase Extraction SPE disks efficiently prepare samples for analysis, crucial for monitoring water, air, and soil quality, and for ensuring the safety and quality of food products. This growing need for reliable analysis across these critical sectors fuels the adoption of SPE disk technology globally.
Advancements in SPE Disk Technology and Automation
Advancements in SPE disk technology and automation are fueling market expansion. Improved disk materials offer enhanced analyte recovery and selectivity. Automated systems streamline sample preparation, reducing manual labor and human error, thereby increasing throughput and consistency across various analytical applications. These innovations make SPE disk methods more efficient, reliable, and accessible for diverse laboratory needs.
Rising Need for High-Throughput and Efficient Sample Preparation
Laboratories across pharmaceuticals, forensics, environmental science, and clinical diagnostics are increasingly challenged by high sample volumes and demanding analytical timelines. Traditional sample preparation methods are often slow and laborious, creating bottlenecks. Solid phase extraction disks offer a streamlined, automated solution to efficiently extract and purify analytes from complex matrices, meeting the growing demand for faster, more reliable, and higher throughput sample preparation to accelerate research and analysis.
Global Solid Phase Extraction SPE Disk Market Restraints
Lack of Standardization in SPE Disk Formats
Varying SPE disk formats among manufacturers hinder widespread adoption. This lack of common specifications creates compatibility issues, forcing users to procure specific equipment or adapt protocols for different brands. It fragments the market, impedes the development of universal automation systems, and increases complexity for laboratories. This inconsistency limits efficiency and prevents seamless method transfer, slowing market expansion.
High Initial Investment for Automated SPE Disk Systems
High initial investment for automated SPE disk systems deters adoption. The substantial upfront cost of equipment, software, and integration presents a significant barrier for many laboratories, particularly smaller ones or those with budget constraints. This financial hurdle limits market penetration despite the systems' efficiency and throughput benefits. Laboratories often prioritize lower-cost, manual, or semi-automated alternatives due to this capital outlay.
Global Solid Phase Extraction SPE Disk Market Opportunities
Expanding SPE Disk Applications for PFAS and Emerging Contaminant Analysis
The global need to accurately detect and quantify PFAS and other emerging contaminants in diverse samples is escalating significantly. SPE disks offer a robust, efficient, and reliable sample preparation method critical for these complex analyses. This presents a significant opportunity to expand their application across environmental, food, and water testing laboratories worldwide. As regulations tighten and public health concerns grow, the sustained demand for advanced, high throughput extraction techniques like SPE disks for these specific pollutants will continue to surge, particularly in rapidly developing regions seeking better environmental monitoring solutions.
Integration of SPE Disks into Automated Lab Workflows for Enhanced Efficiency and Throughput
Integrating SPE disks into automated lab workflows presents a major opportunity. This streamlines sample preparation, a critical analytical bottleneck. By automating SPE, labs achieve superior efficiency, minimizing manual steps and errors. This directly enhances throughput, enabling faster, consistent processing of more samples. Solution providers focusing on seamless integration will meet growing global demand for highly efficient and reliable analytical platforms, particularly in fast developing regions requiring advanced laboratory capabilities.
Global Solid Phase Extraction SPE Disk Market Segmentation Analysis
Key Market Segments
By Application
- •Pharmaceuticals
- •Environmental Testing
- •Food and Beverage
- •Chemical Analysis
- •Clinical Research
By Product Type
- •C18 Disks
- •C8 Disks
- •Strong Anion Exchange Disks
- •Strong Cation Exchange Disks
- •Mixed Mode Disks
By End Use
- •Laboratories
- •Research Institutions
- •Quality Control Facilities
- •Manufacturing Units
By Technique
- •Manual Solid Phase Extraction
- •Automated Solid Phase Extraction
- •Vacuum-Based Solid Phase Extraction
- •Pressure-Based Solid Phase Extraction
Segment Share By Application
Share, By Application, 2025 (%)
- Pharmaceuticals
- Environmental Testing
- Food and Beverage
- Chemical Analysis
- Clinical Research
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Why are C18 Disks dominating the Global Solid Phase Extraction SPE Disk Market?
C18 Disks hold a substantial market share primarily due to their exceptional versatility and efficacy in extracting a wide range of nonpolar and moderately polar compounds. Their robust C18 stationary phase makes them indispensable across diverse applications such as pharmaceutical analysis, environmental contaminant testing, and food safety, where separation of complex matrices is crucial. This broad applicability ensures their consistent demand in laboratories, research institutions, and quality control facilities worldwide.
Which application segment is significantly driving demand for SPE Disks?
The Pharmaceuticals segment is a major driver of demand for SPE disks. In drug discovery, development, and quality control, precise and efficient sample preparation is critical for analyzing active pharmaceutical ingredients, metabolites, and drug residues. SPE disks provide superior cleanup and analyte concentration, reducing matrix interferences and improving detection limits for techniques like LC MS. This necessity for high quality data in pharmaceutical research and manufacturing fuels continuous market growth.
How is the evolution of SPE techniques influencing the market for these disks?
The advancements in SPE techniques, particularly the rise of automated and vacuum based solid phase extraction, significantly shape the market. These techniques offer enhanced throughput, reproducibility, and reduced manual intervention, making sample preparation more efficient for high volume analysis. This shift encourages the adoption of SPE disks that are compatible with these automated and vacuum systems, thereby supporting their expanded use in various end use sectors like research institutions, quality control facilities, and manufacturing units seeking streamlined workflows.
What Regulatory and Policy Factors Shape the Global Solid Phase Extraction SPE Disk Market
The global SPE disk market operates within a highly regulated landscape primarily driven by pharmaceutical, clinical, environmental, and food safety industries. Manufacturers must adhere to stringent quality standards including Good Manufacturing Practices and ISO certifications to ensure product reliability and consistency. Regulatory bodies such as the FDA, EMA, and national environmental protection agencies impose strict guidelines for analytical methods and validation, often specifying or endorsing SPE techniques. Data integrity and method reproducibility are paramount, demanding high performance consumables. Furthermore, international trade policies, customs regulations, and regional chemical substance control acts influence market access and product distribution, creating a complex compliance framework.
What New Technologies are Shaping Global Solid Phase Extraction SPE Disk Market?
Innovations in SPE disk technology center on enhanced sorbent chemistries offering superior selectivity and sensitivity for complex matrices. Emerging technologies include advanced polymeric phases and functionalized silica, driving higher recovery rates and cleaner extracts. Automation and miniaturization are key trends, integrating disks into high throughput systems and robotic platforms, significantly reducing sample preparation time and manual errors. Online SPE LCMS coupling is expanding, streamlining workflows for various analytical applications. Sustainable material development and AI driven method optimization are also gaining traction, promising greener and more efficient extraction processes. These advancements are critical for meeting evolving demands in pharmaceuticals, environmental testing, and clinical diagnostics, propelling significant market expansion.
Global Solid Phase Extraction SPE Disk Market Regional Analysis
Global Solid Phase Extraction SPE Disk Market
Trends, by Region
North America Market
Revenue Share, 2025
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North America dominates the solid phase extraction (SPE) disk market with a significant 38.2% share. This leadership is driven by extensive research and development activities, particularly in pharmaceuticals, biotechnology, and environmental testing. The presence of key market players, advanced healthcare infrastructure, and stringent regulatory frameworks for food and drug safety further propel market growth. Increasing demand for high-throughput and automated sample preparation techniques across diverse applications, coupled with technological advancements in SPE disk technology, solidifies North America's position as a primary revenue generator in the global market.
Europe is a significant player in the Solid Phase Extraction (SPE) disk market, driven by its robust pharmaceutical, biotechnology, and food safety sectors. Germany, France, and the UK are leading contributors, characterized by advanced research infrastructure and stringent regulatory standards for environmental and food testing. The demand for high-throughput and automated sample preparation is increasing, fostering the adoption of SPE disk technology in drug discovery, clinical diagnostics, and contaminant analysis. Nordic countries also show strong growth due to their focus on environmental monitoring and life sciences, solidifying Europe's position as a key regional market for SPE disks.
The Asia Pacific Solid Phase Extraction (SPE) Disk market is experiencing robust growth, propelled by increasing pharmaceutical R&D, rising food safety concerns, and expanding environmental monitoring. Countries like China, India, and Japan are key contributors, driven by a growing biotechnology sector and a surge in contract research organizations. The region's rapid industrialization and improving healthcare infrastructure further fuel demand for advanced separation techniques. Favorable government initiatives supporting scientific research and technological advancements also play a significant role. This dynamic landscape positions Asia Pacific as the fastest-growing region, with a projected CAGR of 9.2%, indicating substantial future expansion in the SPE disk market.
Latin America's SPE disk market is on an upward trajectory, driven by increasing pharmaceutical R&D and food safety regulations. Brazil leads in adoption due to its robust biotech sector and environmental monitoring needs. Mexico's market is expanding with growing demand in clinical diagnostics and agrochemical analysis. Argentina presents significant potential, particularly in academic research and veterinary drug testing. Other nations like Chile and Colombia show steady growth, fueled by rising awareness of advanced sample preparation techniques. Regional expansion is further supported by infrastructure improvements and an increased focus on quality control across various industries.
The Middle East & Africa (MEA) Solid Phase Extraction (SPE) Disk market is experiencing steady growth, driven by increasing pharmaceutical R&D and food safety concerns. South Africa and Saudi Arabia are leading the regional market due to established analytical infrastructures and government investments in healthcare and environmental monitoring. The expansion of contract research organizations (CROs) and growing demand for advanced analytical techniques in clinical diagnostics and environmental analysis further fuel market expansion. While still smaller than developed regions, the rising awareness of SPE Disk advantages for efficient sample preparation across various industries signifies significant future potential in the MEA region.
Top Countries Overview
The United States solid phase extraction disk market is robust, driven by increasing pharmaceutical and environmental testing. Key players offer innovative products, focusing on enhanced sample preparation and efficiency. This competitive landscape fuels advancements in SPE disk technology, supporting various analytical applications across industries.
China's SPE disk market is emerging driven by environmental and food safety demands. Local manufacturers offer cost effective alternatives challenging international brands. Growth is fueled by increased laboratory automation and a rising focus on quality control across various industries positioning China as a key player in solid phase extraction technology.
India's SPE disk market is emerging, driven by analytical needs in pharma, food, and environmental testing. Growing research and industry demand are expanding adoption of these solid phase extraction consumables, impacting global market shares.
Impact of Geopolitical and Macroeconomic Factors
Geopolitical shifts impacting supply chains and raw material costs are a major factor. Trade disputes and regional conflicts can disrupt manufacturing and distribution of SPE disks, leading to price volatility and potential shortages. Regulatory changes, particularly in pharmaceutical and environmental testing sectors, will drive demand and innovation.
Macroeconomic conditions, including global inflation and interest rates, influence investment in R&D and manufacturing capacity. Economic downturns may reduce laboratory budgets, impacting disk purchasing. Conversely, growth in biotechnology and food safety sectors fuels demand, with currency fluctuations affecting import/export competitiveness.
Recent Developments
- March 2025
Agilent Technologies unveiled a new generation of SPE disks featuring advanced polymer chemistry designed for enhanced analyte recovery and reduced matrix effects in complex samples. This product launch aims to cater to the growing demand for more robust and sensitive sample preparation solutions in pharmaceutical and environmental testing.
- September 2024
Thermo Fisher Scientific announced a strategic partnership with a leading laboratory automation provider to integrate their SPE disk technology with automated sample preparation platforms. This collaboration seeks to streamline workflows, increase throughput, and reduce human error in high-volume analytical laboratories.
- July 2025
Biotage completed the acquisition of a niche SPE disk manufacturer specializing in high-capacity, specialized media for specific environmental contaminants. This acquisition expands Biotage's portfolio of advanced SPE solutions and strengthens its market position in the environmental analysis sector.
- April 2025
PALL Corporation introduced a new line of SPE disks specifically engineered for microplastic analysis in water and food samples, addressing a critical emerging analytical challenge. This product launch highlights PALL's commitment to developing innovative solutions for pressing global environmental concerns.
- November 2024
Merck KGaA launched a strategic initiative to invest in R&D for 'green' SPE disk materials, focusing on biodegradable and sustainably sourced polymers. This initiative reflects the industry's growing push towards more environmentally friendly laboratory practices and products.
Key Players Analysis
Key players like PALL Corporation and Agilent Technologies dominate the Global Solid Phase Extraction SPE Disk Market, offering advanced SPE disk technologies for diverse analytical applications. Thermo Fisher Scientific and Merck KGaA provide comprehensive solutions, encompassing innovative sorbent chemistries and automated systems. Strategic initiatives include product line expansions, research and development into novel materials, and collaborations to enhance sample throughput and purification efficiency. Market growth drivers involve increasing demand for improved analytical sensitivity in pharmaceuticals, environmental monitoring, and food safety, alongside the growing adoption of automation in laboratories. Vici Dialysis and Biotage also contribute significantly with specialized SPE disk offerings.
List of Key Companies:
- PALL Corporation
- Vici Dialysis
- Biotage
- Hichrom Limited
- Agilent Technologies
- Thermo Fisher Scientific
- Merck KGaA
- PerkinElmer
- J.T. Baker
- SPEX SamplePrep
- SigmaAldrich
- MilliporeSigma
- Restek Corporation
- LCTech GmbH
- Phenomenex
- Waters Corporation
Report Scope and Segmentation
| Report Component | Description |
|---|---|
| Market Size (2025) | USD 0.38 Billion |
| Forecast Value (2035) | USD 0.75 Billion |
| CAGR (2026-2035) | 7.4% |
| Base Year | 2025 |
| Historical Period | 2020-2025 |
| Forecast Period | 2026-2035 |
| Segments Covered |
|
| Regional Analysis |
|
Table of Contents:
List of Figures
List of Tables
Table 1: Global Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Application, 2020-2035
Table 2: Global Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Product Type, 2020-2035
Table 3: Global Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by End Use, 2020-2035
Table 4: Global Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Technique, 2020-2035
Table 5: Global Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Region, 2020-2035
Table 6: North America Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Application, 2020-2035
Table 7: North America Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Product Type, 2020-2035
Table 8: North America Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by End Use, 2020-2035
Table 9: North America Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Technique, 2020-2035
Table 10: North America Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Country, 2020-2035
Table 11: Europe Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Application, 2020-2035
Table 12: Europe Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Product Type, 2020-2035
Table 13: Europe Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by End Use, 2020-2035
Table 14: Europe Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Technique, 2020-2035
Table 15: Europe Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Country/ Sub-region, 2020-2035
Table 16: Asia Pacific Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Application, 2020-2035
Table 17: Asia Pacific Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Product Type, 2020-2035
Table 18: Asia Pacific Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by End Use, 2020-2035
Table 19: Asia Pacific Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Technique, 2020-2035
Table 20: Asia Pacific Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Country/ Sub-region, 2020-2035
Table 21: Latin America Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Application, 2020-2035
Table 22: Latin America Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Product Type, 2020-2035
Table 23: Latin America Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by End Use, 2020-2035
Table 24: Latin America Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Technique, 2020-2035
Table 25: Latin America Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Country/ Sub-region, 2020-2035
Table 26: Middle East & Africa Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Application, 2020-2035
Table 27: Middle East & Africa Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Product Type, 2020-2035
Table 28: Middle East & Africa Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by End Use, 2020-2035
Table 29: Middle East & Africa Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Technique, 2020-2035
Table 30: Middle East & Africa Solid Phase Extraction SPE Disk Market Revenue (USD billion) Forecast, by Country/ Sub-region, 2020-2035