
Global Orthopedic Biomaterial Market Insights, Size, and Forecast By End Use (Hospitals, Orthopedic Clinics, Ambulatory Surgical Centers, Rehabilitation Centers), By Application (Bone Repair, Joint Reconstruction, Spinal Surgery, Trauma Repair, Dental Applications), By Nature (Synthetic, Natural), By Type (Bioactive Glass, Calcium Phosphate Ceramics, Polymer-based Biomaterials, Metallic Biomaterials, Composites), By Region (North America, Europe, Asia-Pacific, Latin America, Middle East and Africa), Key Companies, Competitive Analysis, Trends, and Projections for 2026-2035
Key Market Insights
Global Orthopedic Biomaterial Market is projected to grow from USD 22.8 Billion in 2025 to USD 45.3 Billion by 2035, reflecting a compound annual growth rate of 7.6% from 2026 through 2035. The orthopedic biomaterial market encompasses a diverse range of natural and synthetic materials used to replace or restore damaged bone and cartilage, ranging from implants and prosthetics to regenerative medicine applications. Key market drivers include the rising global geriatric population, which significantly increases the incidence of age related musculoskeletal disorders such as osteoarthritis and osteoporosis. Furthermore, the growing prevalence of sports injuries, road accidents, and other traumatic events requiring orthopedic interventions continues to fuel demand. Advancements in biomaterial science, particularly in biocompatibility, biodegradability, and mechanical properties, are also propelling market expansion, offering more effective and long lasting solutions for patients. However, the market faces restraints such as the high cost associated with advanced biomaterials and complex regulatory approval processes, which can prolong time to market for innovative products. Moreover, the risk of implant failure and associated revision surgeries, though decreasing with technological advancements, remains a concern.
Global Orthopedic Biomaterial Market Value (USD Billion) Analysis, 2025-2035

2025 - 2035
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Important trends shaping the market include the shift towards personalized medicine and patient specific implants, leveraging technologies like 3D printing for customized solutions. The increasing adoption of biodegradable and bioresorbable materials, which eliminate the need for secondary removal surgeries, represents another significant trend. Furthermore, the growing focus on combination products incorporating biomaterials with growth factors or stem cells for enhanced regenerative capabilities is gaining traction. North America stands as the dominant region in the global orthopedic biomaterial market. This prominence is attributable to a well developed healthcare infrastructure, high healthcare expenditure, significant research and development activities, and the presence of major market players. The region benefits from early adoption of advanced medical technologies and a large pool of patients seeking advanced orthopedic care. Conversely, Asia Pacific is identified as the fastest growing region. This rapid growth is driven by improving healthcare access, increasing disposable incomes, a large patient pool, and rising awareness about advanced orthopedic treatments. Government initiatives to improve healthcare infrastructure and the expanding medical tourism sector further contribute to the region's accelerated market expansion.
Opportunities within the market abound, particularly in the development of smart biomaterials with sensing capabilities and drug delivery systems for localized therapeutic effects. The expanding scope of applications beyond traditional joint replacement, including spinal fusion, dental implants, and maxillofacial reconstruction, also presents significant growth avenues. The leading segment, Metallic Biomaterials, continues to hold a substantial market share due to their superior strength, durability, and proven track record in various orthopedic applications, including joint replacements and fracture fixation. Key players in this competitive landscape include Globus Medical, CeramTec, Osseon, NuVasive, Materialise, DePuy Synthes, Amedica Corporation, B. Braun Melsungen, Orthofix Medical, and Zimmer Biomet. These companies are actively engaged in strategic initiatives such as mergers and acquisitions, collaborations, and product innovation to strengthen their market position and expand their product portfolios. Their strategies often focus on developing next generation biomaterials, expanding into emerging markets, and investing in research and development to address unmet clinical needs and introduce novel solutions.
Quick Stats
Market Size (2025):
USD 22.8 BillionProjected Market Size (2035):
USD 45.3 BillionLeading Segment:
Metallic Biomaterials (45.2% Share)Dominant Region (2025):
North America (45.2% Share)CAGR (2026-2035):
7.6%
What is Orthopedic Biomaterial?
Orthopedic biomaterials are substances engineered to interact with biological systems for orthopedic purposes. They replace or assist damaged bone, cartilage, ligaments, and tendons. These materials can be metals, polymers, ceramics, or composites, designed for biocompatibility, mechanical strength, and corrosion resistance. Their significance lies in enabling joint replacements, fracture fixation, spinal implants, and tissue regeneration. Applications range from hip and knee prostheses to screws, plates, and scaffolds for bone healing, improving patient mobility and quality of life by restoring musculoskeletal function and repairing tissue damage.
What are the Trends in Global Orthopedic Biomaterial Market
Bioprinted Implants Reshaping Orthopedics
Smart Biomaterials Revolutionizing Joint Repair
Personalized Biomaterial Solutions for Patients
Sustainable Orthopedic Biomaterials Gain Traction
Bioprinted Implants Reshaping Orthopedics
Bioprinted implants are transforming orthopedics by enabling the creation of patient specific biomaterials with enhanced regenerative properties. This trend leverages living cells and biomaterials to fabricate functional tissues and organs, offering superior integration and durability compared to traditional implants. It promises personalized solutions for complex bone and cartilage defects, accelerating recovery and improving long term outcomes for orthopedic patients globally.
Smart Biomaterials Revolutionizing Joint Repair
Smart biomaterials are transforming joint repair by offering advanced solutions beyond traditional implants. These innovative materials facilitate better integration, stimulate tissue regeneration, and precisely deliver therapeutic agents. This revolution significantly improves patient outcomes, offering customisable and more durable repairs for damaged joints worldwide. Their bioactivity and adaptability are key drivers in orthopedic advancements.
Personalized Biomaterial Solutions for Patients
This trend signifies a shift towards customizing biomaterials for individual patients. Instead of generic implants, solutions are designed to match a patient's unique anatomy, physiology, and disease characteristics. This personalization, often enabled by advanced manufacturing and diagnostic tools, optimizes implant performance, integration with host tissues, and long term success in orthopedic applications, improving patient outcomes and quality of life.
Sustainable Orthopedic Biomaterials Gain Traction
Eco conscious orthopedic biomaterials are increasingly preferred. This trend highlights a shift towards environmentally friendly, biocompatible, and biodegradable materials for implants. Innovations focus on reducing surgical waste and improving patient outcomes through sustainable solutions. Demand for renewable and natural origin biomaterials is rising, driven by their lower environmental impact and promising clinical performance in orthopedic applications worldwide.
What are the Key Drivers Shaping the Global Orthopedic Biomaterial Market
Rising Incidence of Orthopedic Conditions and Trauma
Advancements in Biomaterial Technology and Product Innovation
Growing Geriatric Population and Demand for Joint Replacement
Increasing Adoption of Minimally Invasive Surgical Procedures
Rising Incidence of Orthopedic Conditions and Trauma
An aging global population and increasing prevalence of conditions like osteoporosis and osteoarthritis are fueling a rise in orthopedic ailments. Additionally, the growing incidence of sports related injuries and vehicular accidents contribute significantly to the demand for orthopedic biomaterials. These factors necessitate more surgical interventions requiring implants and other biomaterial solutions.
Advancements in Biomaterial Technology and Product Innovation
Progress in biomaterial science including new ceramics, metals, and polymers drives better orthopedic solutions. These innovations lead to advanced implants with improved biocompatibility, durability, and functional performance. This enables development of more effective and specialized products like bioresorbable scaffolds and smart materials, expanding treatment options and market reach.
Growing Geriatric Population and Demand for Joint Replacement
Aging populations globally are experiencing increased musculoskeletal conditions like osteoarthritis. This drives a significant surge in demand for joint replacement surgeries, particularly knees and hips, to restore mobility and improve quality of life. Orthopedic biomaterials are crucial for these procedures, forming the foundation of implants and contributing to the market's expansion.
Increasing Adoption of Minimally Invasive Surgical Procedures
Growing preference for less invasive surgeries significantly boosts orthopedic biomaterial demand. These procedures require specialized, high-performance biomaterials for smaller incisions, reduced patient trauma, faster recovery, and improved functional outcomes. This shift drives the need for advanced implants and devices compatible with these minimally disruptive surgical techniques, expanding the market for bone grafts, substitutes, and fixation products.
Global Orthopedic Biomaterial Market Restraints
Stringent Regulatory Hurdles for Novel Biomaterials
Developing new orthopedic biomaterials faces significant delays and expense due to rigorous regulatory scrutiny. Manufacturers must navigate extensive testing, clinical trials, and documentation requirements to prove safety and efficacy. This stringent process for novel materials increases research and development costs, prolongs market entry, and can deter investment. It creates a high barrier, slowing innovation and the introduction of advanced solutions to the global market.
High R&D Costs and Prolonged Time-to-Market for Advanced Materials
Developing advanced orthopedic biomaterials requires substantial investment and extensive research. This translates to high R&D costs for companies. Furthermore, the rigorous testing and regulatory approval processes prolong the time it takes for these innovative materials to reach the market. This extended development cycle and significant financial outlay limit the rapid introduction of cutting edge biomaterials, impeding market growth and innovation.
Global Orthopedic Biomaterial Market Opportunities
Leveraging Bio-Active and Regenerative Technologies for Advanced Orthopedic Repair
The opportunity lies in developing and commercializing advanced biomaterials that actively stimulate bone and tissue regeneration for superior orthopedic repair. Leveraging bioactive compounds, growth factors, and smart scaffolds, these technologies accelerate healing, enhance tissue integration, and provide durable patient outcomes. This addresses unmet needs in complex fractures, degenerative conditions, and sports injuries by promoting natural restoration. It represents a significant shift from passive implants to active, regenerative solutions, promising reduced recovery times and improved quality of life. This innovation is poised to capture substantial demand in the evolving global orthopedic biomaterial market.
Growth in Sports Medicine and Trauma Surgery Fueling Demand for Specialized Biomaterials
Rising global participation in sports and an increase in traumatic injuries are significantly boosting the need for advanced surgical interventions. This expanding volume of sports medicine and trauma cases directly fuels a substantial demand for highly specialized orthopedic biomaterials. These advanced materials are crucial for effective bone regeneration, tissue repair, and robust implant fixation, leading to better patient outcomes and faster recovery. Manufacturers have a prime opportunity to innovate and supply high performance, biocompatible solutions to meet these evolving clinical needs across the globe.
Global Orthopedic Biomaterial Market Segmentation Analysis
Key Market Segments
By Type
- •Bioactive Glass
- •Calcium Phosphate Ceramics
- •Polymer-based Biomaterials
- •Metallic Biomaterials
- •Composites
By Application
- •Bone Repair
- •Joint Reconstruction
- •Spinal Surgery
- •Trauma Repair
- •Dental Applications
By End Use
- •Hospitals
- •Orthopedic Clinics
- •Ambulatory Surgical Centers
- •Rehabilitation Centers
By Nature
- •Synthetic
- •Natural
Segment Share By Type
Share, By Type, 2025 (%)
- Metallic Biomaterials
- Polymer-based Biomaterials
- Calcium Phosphate Ceramics
- Composites
- Bioactive Glass

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Why are Metallic Biomaterials dominating the Global Orthopedic Biomaterial Market?
Metallic biomaterials lead the market primarily due to their exceptional mechanical strength, durability, and biocompatibility, making them ideal for high-stress applications such as joint reconstruction and spinal surgery. Their proven track record in long-term implant stability and resistance to corrosion further solidifies their prominent position across various orthopedic procedures, addressing critical needs for robust and reliable solutions.
How do diverse applications influence the demand for different biomaterial types?
The varied applications significantly shape biomaterial demand. For instance, joint reconstruction and spinal surgery predominantly rely on the robust properties of metallic and some polymer-based biomaterials. Conversely, bone repair and trauma often see the utilization of bioactive glass or calcium phosphate ceramics, which promote osteointegration and bone regeneration. Dental applications also necessitate specific materials that balance strength with aesthetic and biological integration.
In what ways do end-use settings impact the adoption of orthopedic biomaterials?
End-use settings directly influence the types and volume of biomaterials adopted. Hospitals, with their comprehensive surgical capabilities, are major consumers across all biomaterial types for complex procedures. Orthopedic clinics and ambulatory surgical centers drive demand for less invasive or routine interventions, often utilizing a range of materials suitable for efficient outpatient care. Rehabilitation centers, while not directly implanting, influence post-surgical biomaterial performance requirements through patient recovery protocols.
What Regulatory and Policy Factors Shape the Global Orthopedic Biomaterial Market
The global orthopedic biomaterial market faces a complex and highly regulated environment. Key bodies like the US FDA, European Union MDR, and Asian regulators enforce stringent requirements for product safety, efficacy, and biocompatibility. Extensive preclinical and clinical evidence is mandatory for market approval, varying significantly across regions. Post market surveillance, traceability, and quality management systems are increasingly critical. Evolving regulations, notably the EU Medical Device Regulation, elevate compliance burdens, demanding robust documentation and significant investment. This stringent framework ensures high product standards and patient safety but also extends development timelines and creates substantial barriers to market entry. Consequently, manufacturers prioritize comprehensive regulatory strategies and continuous adaptation to evolving global policies.
What New Technologies are Shaping Global Orthopedic Biomaterial Market?
The orthopedic biomaterial market is rapidly advancing through transformative innovations. Additive manufacturing, particularly 3D printing, enables personalized implants with complex structures, improving patient specificity and integration. Bioactive materials like enhanced ceramics and polymers are crucial, actively promoting bone regeneration and reducing healing times. Emerging smart biomaterials offer sophisticated functionalities, including controlled drug release and self healing properties, significantly improving post operative care. Nanotechnology is optimizing material strength and biocompatibility, leading to more durable and effective solutions. Furthermore, advancements in resorbable materials and tissue engineering scaffolds, often integrated with regenerative medicine techniques, are minimizing revision surgeries and restoring natural tissue function across diverse orthopedic applications.
Global Orthopedic Biomaterial Market Regional Analysis
Global Orthopedic Biomaterial Market
Trends, by Region

North America Market
Revenue Share, 2025
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North America dominates the global orthopedic biomaterial market with a substantial 45.2% share, driven by advanced healthcare infrastructure, high prevalence of orthopedic conditions, and rapid adoption of innovative biomaterials. The region benefits from significant R&D investments, a strong presence of key market players, and favorable reimbursement policies. Increased orthopedic procedures, especially among an aging population, coupled with a focus on personalized medicine and biomaterial-based implants, further fuel market expansion. Stringent regulatory frameworks ensure high-quality product development, reinforcing North America's leadership in this critical medical technology sector.
Europe is a key region in the orthopedic biomaterial market, driven by its aging population and advanced healthcare infrastructure. Germany, France, and the UK lead in adopting innovative biomaterials, particularly in spine and joint reconstruction. Regulatory bodies like EMA ensure high standards, fostering a market for premium, biocompatible materials. Focus on resorbable and bio-active materials is increasing, reflecting a shift towards regenerative solutions. Localized manufacturing and R&D further solidify Europe’s position as a hub for orthopedic biomaterial innovation, despite pricing pressures from national healthcare systems. Market growth is stable, underpinned by continuous technological advancements.
The Asia Pacific orthopedic biomaterial market is the fastest-growing region, projected at a 9.2% CAGR. This surge is fueled by several factors. Rapidly aging populations across countries like Japan, China, and South Korea are driving increased demand for orthopedic procedures. Improving healthcare infrastructure and rising disposable incomes further contribute to greater accessibility and adoption of advanced biomaterials. Additionally, a growing prevalence of orthopedic conditions, coupled with increasing awareness of innovative treatment options, stimulates market expansion. Local manufacturing capabilities and government initiatives promoting medical tourism also play a significant role in the region's robust growth.
Latin America's orthopedic biomaterial market thrives on increasing healthcare access and an aging population. Brazil leads with robust demand for reconstructive and trauma care. Mexico benefits from growing medical tourism and government healthcare investments. Colombia and Chile show steady growth, driven by expanding insurance coverage and sophisticated medical infrastructure. The region exhibits high demand for both traditional metallic and advanced ceramic/polymer biomaterials. Local manufacturing is emerging, but imports, particularly high-value biomaterials, dominate. Economic stability and healthcare policy reforms are key drivers, while currency fluctuations and varying regulatory landscapes present challenges. Regional players are focusing on affordability and local adaptations.
The Middle East & Africa orthopedic biomaterial market is rapidly expanding, driven by increasing healthcare infrastructure development and rising orthopedic surgical volumes, particularly joint replacements and trauma fixation. Regional growth is further bolstered by government initiatives promoting medical tourism and local manufacturing capabilities in countries like UAE and Saudi Arabia. However, price sensitivity and varying regulatory landscapes across diverse nations present challenges. Demand for both metallic and ceramic biomaterials remains strong, with a notable rise in demand for advanced polymer and composite materials. Improved access to specialized orthopedic care in urban centers also contributes significantly to market expansion.
Top Countries Overview
The United States leads the global orthopedic biomaterial market, driven by advanced research and development and a large patient population. Innovation in biocompatible materials and regenerative medicine is crucial for market growth, addressing the rising demand for effective orthopedic solutions and technological advancements.
China significantly impacts the global orthopedic biomaterial market. Its domestic companies are rapidly advancing, focusing on innovation and localized production. This growth influences global trends, offering both challenges and opportunities for international players.
India's growing healthcare demand fuels orthopedic biomaterial market expansion. Domestic manufacturing reduces import reliance. It is a key player in research and development, contributing significantly to innovation and affordability globally.
Impact of Geopolitical and Macroeconomic Factors
Geopolitical shifts like trade disputes and intellectual property protection alter supply chains for specialized biomaterials. Regional conflicts can disrupt raw material sourcing and manufacturing, especially for advanced ceramics or polymers. Increased scrutiny on medical device quality and country of origin creates compliance challenges, impacting market entry and operational costs. Regulatory divergence between major economies further complicates market access and product development timelines.
Macroeconomic trends significantly shape demand. Inflationary pressures increase production costs, potentially leading to higher prices and reduced consumer purchasing power for elective procedures. Interest rate hikes impact hospital expansion and investment in new technologies. Favorable government healthcare spending policies and an aging global population with greater access to healthcare are key growth drivers, particularly in emerging economies.
Recent Developments
- March 2025
Globus Medical announced a strategic partnership with a leading additive manufacturing firm to accelerate the development of personalized orthopedic implants. This collaboration aims to leverage advanced 3D printing technologies to create patient-specific solutions with enhanced biocompatibility and mechanical properties.
- January 2025
DePuy Synthes launched its new generation of biodegradable polymer screws for orthopedic trauma applications. These screws are designed to gradually resorb in the body, eliminating the need for a second surgery for hardware removal and potentially reducing patient recovery time.
- February 2025
Zimmer Biomet acquired a specialized startup focused on advanced ceramic biomaterials for joint replacement. This acquisition strengthens Zimmer Biomet's portfolio in highly durable and wear-resistant implant materials, addressing a growing demand for longer-lasting solutions in arthroplasty.
- April 2025
Materialise expanded its partnership with Orthofix Medical to integrate its advanced surgical planning software with Orthofix's innovative external fixation systems. This collaboration aims to enhance surgical precision and patient outcomes by providing surgeons with more intuitive and accurate pre-operative planning tools.
- May 2025
Amedica Corporation received expanded FDA clearance for its silicon nitride interbody fusion devices to include a broader range of spinal indications. This approval allows Amedica to address a larger patient population seeking improved fusion rates and reduced subsidence compared to traditional PEEK implants.
Key Players Analysis
Key players in the global orthopedic biomaterial market showcase diverse strengths driving innovation and market growth. Zimmer Biomet and DePuy Synthes, industry giants, offer comprehensive portfolios across various biomaterial types, leveraging extensive R&D and global distribution for sustained market dominance. Smaller innovators like Globus Medical and Orthofix Medical focus on niche segments, often introducing advanced materials and fixation solutions. CeramTec specializes in high performance ceramics, while Materialise is a leader in 3D printing for patient specific implants, showcasing technology driven differentiation. Amedica Corporation contributes with silicon nitride biomaterials, emphasizing biocompatibility and osteoinductivity. Strategic initiatives include acquisitions for portfolio expansion, collaborative research for next generation materials, and investments in additive manufacturing. These efforts address the growing demand for personalized medicine, minimally invasive procedures, and improved implant longevity, fueling market expansion.
List of Key Companies:
- Globus Medical
- CeramTec
- Osseon
- NuVasive
- Materialise
- DePuy Synthes
- Amedica Corporation
- B. Braun Melsungen
- Orthofix Medical
- Zimmer Biomet
- Haptiq
- Medtronic
- Stryker
- Smith & Nephew
- Invibio
Report Scope and Segmentation
| Report Component | Description |
|---|---|
| Market Size (2025) | USD 22.8 Billion |
| Forecast Value (2035) | USD 45.3 Billion |
| CAGR (2026-2035) | 7.6% |
| Base Year | 2025 |
| Historical Period | 2020-2025 |
| Forecast Period | 2026-2035 |
| Segments Covered |
|
| Regional Analysis |
|
Table of Contents:
List of Figures
List of Tables
Table 1: Global Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Type, 2020-2035
Table 2: Global Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Application, 2020-2035
Table 3: Global Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by End Use, 2020-2035
Table 4: Global Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Nature, 2020-2035
Table 5: Global Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Region, 2020-2035
Table 6: North America Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Type, 2020-2035
Table 7: North America Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Application, 2020-2035
Table 8: North America Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by End Use, 2020-2035
Table 9: North America Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Nature, 2020-2035
Table 10: North America Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Country, 2020-2035
Table 11: Europe Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Type, 2020-2035
Table 12: Europe Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Application, 2020-2035
Table 13: Europe Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by End Use, 2020-2035
Table 14: Europe Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Nature, 2020-2035
Table 15: Europe Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Country/ Sub-region, 2020-2035
Table 16: Asia Pacific Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Type, 2020-2035
Table 17: Asia Pacific Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Application, 2020-2035
Table 18: Asia Pacific Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by End Use, 2020-2035
Table 19: Asia Pacific Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Nature, 2020-2035
Table 20: Asia Pacific Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Country/ Sub-region, 2020-2035
Table 21: Latin America Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Type, 2020-2035
Table 22: Latin America Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Application, 2020-2035
Table 23: Latin America Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by End Use, 2020-2035
Table 24: Latin America Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Nature, 2020-2035
Table 25: Latin America Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Country/ Sub-region, 2020-2035
Table 26: Middle East & Africa Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Type, 2020-2035
Table 27: Middle East & Africa Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Application, 2020-2035
Table 28: Middle East & Africa Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by End Use, 2020-2035
Table 29: Middle East & Africa Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Nature, 2020-2035
Table 30: Middle East & Africa Orthopedic Biomaterial Market Revenue (USD billion) Forecast, by Country/ Sub-region, 2020-2035
