Global L-Pyroglutamic Acid Market Insights, Size, and Forecast By Grade (Food Grade, Pharmaceutical Grade, Industrial Grade), By Application (Pharmaceuticals, Cosmetics, Food & Beverages, Nutraceuticals), By Form (Powder, Liquid, Granule), By Distribution Channel (Online, Offline, Direct Sales), By Region (North America, Europe, Asia-Pacific, Latin America, Middle East and Africa), Key Companies, Competitive Analysis, Trends, and Projections for 2026-2035
Key Market Insights
Global L-Pyroglutamic Acid Market is projected to grow from USD 0.21 Billion in 2025 to USD 0.38 Billion by 2035, reflecting a compound annual growth rate of 6.2% from 2026 through 2035. L-Pyroglutamic acid, a naturally occurring amino acid derivative, is gaining significant traction across various industries due to its unique properties as a humectant, antioxidant, and chelating agent. This market overview encompasses the global landscape, analyzing the acid's diverse applications, forms, grades, and distribution channels. The increasing consumer demand for natural and effective ingredients in personal care products, particularly those offering moisturizing and anti-aging benefits, is a primary driver for market expansion. Furthermore, its utility in pharmaceuticals as an intermediate and its growing adoption in food and beverage as a flavor enhancer and nutrient supplement are contributing to its robust growth. However, market growth could be constrained by the complex and costly manufacturing processes, leading to higher product prices and potentially limited widespread adoption in certain cost-sensitive applications. Regulatory hurdles and the availability of substitute ingredients also pose challenges to market penetration.
Global L-Pyroglutamic Acid Market Value (USD Billion) Analysis, 2025-2035
2025 - 2035
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A key trend shaping the L-Pyroglutamic Acid market is the rising focus on sustainable and green chemistry practices, pushing manufacturers towards bio-based and environmentally friendly production methods. The expansion of the nutraceutical industry, driven by an aging global population and increasing health consciousness, presents significant opportunities for L-Pyroglutamic acid due to its potential health benefits. The dominant market position is held by Asia Pacific, primarily due to the rapid expansion of the cosmetics and personal care industries in countries like China and India, coupled with rising disposable incomes and a growing consumer base for premium beauty products. This region is also identified as the fastest growing, propelled by burgeoning industrialization, increasing investments in research and development, and a strong manufacturing base for pharmaceutical and chemical products. The growing demand for innovative ingredients in diverse end-use sectors, especially in cosmetic formulations and functional foods, further fuels the growth trajectory in Asia Pacific.
The competitive landscape of the L-Pyroglutamic Acid market features prominent players such as Zhangjiagang Huachang Chemical, Ajinomoto Co, Evonik Industries, Hubei Huitian New Materials, Hubei Zhengjin Xinyuan Chemical, Tianjin Kermel Chemical, SABIC, Loba Chemie, Zhejiang Jianye Chemical, and Merck Group. These companies are actively engaged in strategic initiatives including capacity expansion, product innovation, and mergers and acquisitions to strengthen their market presence and cater to the evolving demands of end-users. For instance, some players are focusing on developing high-purity grades of L-Pyroglutamic acid specifically for pharmaceutical applications, while others are investing in research to explore new applications in emerging sectors. The leading segment, by application, is Cosmetics, underscoring the vital role L-Pyroglutamic acid plays in skincare, haircare, and other personal care formulations due to its excellent moisturizing and skin-conditioning properties. This segment's dominance is expected to persist, driven by continuous innovation in cosmetic product development and increasing consumer awareness regarding ingredient efficacy.
Quick Stats
Market Size (2025):
USD 0.21 BillionProjected Market Size (2035):
USD 0.38 BillionLeading Segment:
Cosmetics (42.8% Share)Dominant Region (2025):
Asia Pacific (41.8% Share)CAGR (2026-2035):
6.2%
What is L-Pyroglutamic Acid?
L-Pyroglutamic acid is a cyclic amino acid derived from glutamic acid, forming a lactam. It is naturally occurring in various biological systems and is an important chiral building block in organic synthesis. Its significance spans several fields. In biochemistry, it is a metabolic intermediate and a component of some proteins. Industrially, it serves as a precursor for polymers, pharmaceuticals, and agricultural chemicals, valued for its biodegradability and non toxicity. Its applications include cosmetics as a humectant and skin conditioning agent and as a chiral auxiliary in asymmetric synthesis, highlighting its versatility and unique chemical properties.
What are the Trends in Global L-Pyroglutamic Acid Market
Cosmeceutical Surge Driving L Pyroglutamic Acid Demand
Sustainable Sourcing Innovations for PGA Growth
Nutraceutical Expansion Boosting L Pyroglutamic Acid Uptake
Personalized Skincare Fueling L PGA Applications
Cosmeceutical Surge Driving L Pyroglutamic Acid Demand
The cosmeceutical industry's rapid expansion, fueled by consumer demand for science backed skincare, is increasingly incorporating L pyroglutamic acid. Its efficacy as a humectant and skin conditioning agent drives this demand. As more beauty brands formulate products targeting hydration and anti aging, the ingredient's popularity surges, directly impacting the global L pyroglutamic acid market growth.
Sustainable Sourcing Innovations for PGA Growth
Sustainable sourcing innovations are crucial for L Pyroglutamic Acid market growth. As demand from the pharmaceutical, food, and cosmetic industries rises, focus shifts to eco friendly production. New enzymatic and fermentation routes offer greener alternatives to chemical synthesis. These innovations enhance product quality, reduce environmental impact, and improve supply chain resilience, attracting manufacturers prioritizing ethical and sustainable practices for long term PGA market expansion.
Nutraceutical Expansion Boosting L Pyroglutamic Acid Uptake
Nutraceutical growth fuels L pyroglutamic acid demand. Consumers seek natural health products featuring this amino acid for its skin benefits and cognitive support. The clean label trend further boosts its appeal, driving increased uptake in the global market. Manufacturers are formulating more products with L pyroglutamic acid, recognizing its value as an active ingredient in this expanding sector.
Personalized Skincare Fueling L PGA Applications
Personalized skincare increasingly tailors products to individuals. Many custom formulations incorporate L PGA for its moisturizing and skin soothing properties. This demand for bespoke skincare solutions, driven by consumer preference for efficacy and tailored ingredients, directly translates into more diverse applications for L PGA within cosmetic formulations globally, fueling its market expansion.
What are the Key Drivers Shaping the Global L-Pyroglutamic Acid Market
Rising Demand for Amino Acids in Pharmaceutical and Nutraceutical Industries
Expanding Applications of L-Pyroglutamic Acid in Cosmetics and Personal Care Products
Technological Advancements in Fermentation and Production Processes
Increasing Awareness and Adoption of Functional Ingredients in Food and Beverage Sector
Rising Demand for Amino Acids in Pharmaceutical and Nutraceutical Industries
Growing awareness of health benefits and functional properties of amino acids fuels their use in medicines and supplements. L Pyroglutamic Acid, a vital amino acid derivative, is increasingly sought after for its role in various pharmaceutical formulations and nutraceutical products, driving its market expansion. This reflects a broad industry shift towards natural and bio-active ingredients for improved human well-being.
Expanding Applications of L-Pyroglutamic Acid in Cosmetics and Personal Care Products
L Pyroglutamic acid's versatility in cosmetics is driving market growth. Its hydrating, skin balancing, and anti aging properties are increasingly incorporated into moisturizers, serums, and hair care. This wider adoption across diverse personal care formulations caters to rising consumer demand for effective and natural ingredients.
Technological Advancements in Fermentation and Production Processes
Innovations in fermentation technology and production methods are optimizing L Pyroglutamic acid synthesis. New strains, bioreactor designs, and process controls enhance yield, purity, and efficiency. This reduces costs and expands production capabilities, making L Pyroglutamic acid more accessible and affordable for diverse applications. These advancements are fueling market growth by enabling broader industrial adoption and meeting increasing demand.
Increasing Awareness and Adoption of Functional Ingredients in Food and Beverage Sector
Growing consumer understanding of health benefits offered by functional foods and beverages drives demand for L Pyroglutamic Acid. This ingredient enhances flavor and acts as a humectant in products targeting immunity, digestion, and cognitive health. As more consumers seek these fortified options, manufacturers increasingly incorporate L Pyroglutamic Acid, boosting its market presence.
Global L-Pyroglutamic Acid Market Restraints
Lack of Standardized Regulatory Frameworks for L-Pyroglutamic Acid Applications
Inconsistent global regulations for L-Pyroglutamic acid hinder its widespread adoption. Varying national standards for purity, applications, and safety assessments create complexities for manufacturers and limit market expansion. This absence of uniform guidelines complicates international trade and product development, preventing companies from leveraging the full potential of L-Pyroglutamic acid in diverse industries. Manufacturers face increased costs and delays navigating multiple approval processes, stifling innovation and market penetration.
High Production Costs and Limited Scalability of L-Pyroglutamic Acid Synthesis
High production costs for L-Pyroglutamic acid synthesis stem from complex multi-step chemical reactions requiring specialized equipment and expensive raw materials. This significantly increases manufacturing expenses, hindering price competitiveness. Furthermore, current synthesis methods often involve batch processing, making it difficult to scale up production to meet increasing demand without substantial capital investment. These factors limit market penetration and restrict wider adoption of L-Pyroglutamic acid in various applications, impeding overall market growth and expansion.
Global L-Pyroglutamic Acid Market Opportunities
L-Pyroglutamic Acid: Capitalizing on the Surge in Natural & Anti-Aging Skincare Demand
L-Pyroglutamic Acid offers a prime opportunity leveraging the surge in natural and anti-aging skincare demand. Consumers increasingly seek naturally derived ingredients for effective hydration and youthful skin. As a key component of the skin's natural moisturizing factors, L-Pyroglutamic Acid perfectly fits this trend, providing superior hydration and anti-aging benefits. Developing innovative products featuring this natural compound, particularly in the fast growing Asia Pacific region, allows companies to capitalize on strong preferences for clean beauty and high performance anti-aging solutions.
L-Pyroglutamic Acid: Essential Building Block for Next-Generation Pharmaceutical Intermediates
L-Pyroglutamic acid offers a compelling opportunity as a crucial building block for developing next-generation pharmaceutical intermediates. Its essential role stems from its unique properties, making it vital for synthesizing advanced drug compounds and innovative therapeutics. This includes specialized medicines for complex diseases and novel formulations. The surging demand, particularly within the fast growing Asia Pacific region's pharmaceutical industry, underscores its strategic value. L-PGA is therefore positioned as a foundational component driving substantial future advancements in medicinal chemistry and drug discovery.
Global L-Pyroglutamic Acid Market Segmentation Analysis
Key Market Segments
By Application
- •Pharmaceuticals
- •Cosmetics
- •Food & Beverages
- •Nutraceuticals
By Form
- •Powder
- •Liquid
- •Granule
By Grade
- •Food Grade
- •Pharmaceutical Grade
- •Industrial Grade
By Distribution Channel
- •Online
- •Offline
- •Direct Sales
Segment Share By Application
Share, By Application, 2025 (%)
- Cosmetics
- Pharmaceuticals
- Food & Beverages
- Nutraceuticals
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Why is the Cosmetics segment dominating the Global L-Pyroglutamic Acid Market?
The significant share held by Cosmetics stems from L-Pyroglutamic Acid's exceptional properties as a natural moisturizing factor component. Its ability to effectively hydrate skin, enhance elasticity, and offer mild exfoliating benefits makes it a highly sought after ingredient in skincare formulations, anti aging products, and hair care solutions. Consumers' increasing demand for science backed, high performing cosmetic ingredients fuels this segment's primary position.
Which form factor is most crucial for the broad application of L-Pyroglutamic Acid?
The Powder form factor likely holds significant importance across various applications. Its stability, ease of handling, and precise dosing capabilities make it ideal for incorporation into dry mixes, capsules, and a wide array of cosmetic and nutraceutical formulations. While liquid forms offer convenience for certain end products, the versatility and cost effectiveness of powder contribute significantly to its widespread adoption by manufacturers in diverse industries.
How do varying grades influence the L-Pyroglutamic Acid market's accessibility and applications?
The distinction between Food Grade, Pharmaceutical Grade, and Industrial Grade is pivotal for market segmentation. Pharmaceutical Grade L-Pyroglutamic Acid adheres to stringent purity standards, enabling its use in medicinal applications where safety and efficacy are paramount. Food Grade allows its incorporation into functional foods and beverages, while Industrial Grade caters to less sensitive uses. These specific grade requirements dictate market access and suitability for different regulated industries.
What Regulatory and Policy Factors Shape the Global L-Pyroglutamic Acid Market
The global L-Pyroglutamic Acid market navigates a multifaceted regulatory landscape. Regulations primarily address its applications in food, cosmetics, and pharmaceuticals. Agencies like the US FDA, European Union authorities, and bodies in Japan and China enforce stringent purity, safety, and labeling requirements. For food use, approvals often depend on Generally Recognized As Safe GRAS status or specific food additive listings. Cosmetic applications are subject to ingredient safety assessments and usage limits. Pharmaceutical grades adhere to pharmacopeial standards and Good Manufacturing Practices. Compliance with chemical registration schemes, such as REACH in Europe, significantly impacts market access and operational costs, ensuring product quality and consumer safety worldwide.
What New Technologies are Shaping Global L-Pyroglutamic Acid Market?
The L-Pyroglutamic Acid market is undergoing significant transformation through innovation. Emerging technologies are largely focused on enhancing production sustainability and efficiency. Advanced biotechnology, including optimized microbial fermentation with engineered strains, is improving yields and purity while reducing environmental impact. Green chemistry principles are increasingly applied, developing solvent free or enzyme catalyzed synthesis routes for more eco friendly manufacturing. Artificial intelligence and machine learning are pivotal in process optimization, predicting reaction kinetics, and identifying novel applications, particularly in functional foods, pharmaceuticals, and high end cosmetics. Enhanced purification methods leveraging membrane technology ensure superior product quality. These innovations promise to expand market reach and create diverse product offerings.
Global L-Pyroglutamic Acid Market Regional Analysis
Global L-Pyroglutamic Acid Market
Trends, by Region
Asia-Pacific Market
Revenue Share, 2025
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North America, particularly the US and Canada, represents a mature but growing market for L-Pyroglutamic Acid. Demand is primarily driven by the expanding cosmetics and personal care industries, leveraging its humectant and skin-conditioning properties. The increasing awareness of natural and clean-label ingredients further boosts its adoption. The pharmaceutical sector also contributes, albeit to a lesser extent, utilizing it as a chiral building block and a component in certain drug formulations. Research and development activities, coupled with a robust manufacturing infrastructure, further strengthen North America’s position in the global L-Pyroglutamic Acid market. Regulatory landscape also favors its use in diverse applications.
Europe’s L-Pyroglutamic Acid market exhibits robust growth, driven by its advanced pharmaceutical and cosmetic industries. Germany and France lead in demand due to strong R&D and manufacturing capabilities, particularly in peptide synthesis and anti-aging formulations. The UK and Italy also contribute significantly, with increasing applications in specialty chemicals and nutritional supplements. Regulatory support for natural ingredients further fuels market expansion. While a mature market, innovation in bio-based production and expanding applications in agriculture (as a plant growth regulator) promise continued growth. Pricing remains competitive, influenced by raw material costs and import/export dynamics with Asia.
Asia Pacific dominates the global L-Pyroglutamic Acid market with a commanding 41.8% share, driven by robust demand from the pharmaceuticals, cosmetics, and food industries. The region is also the fastest growing, projected to expand at an impressive CAGR of 9.2%. This rapid growth is fueled by increasing healthcare expenditure, a burgeoning middle class, and the expanding personal care sector in countries like China, India, and Japan. Significant investments in research and development further bolster the region's strong market position and future growth prospects.
Latin America's L-Pyroglutamic Acid market is nascent but growing, driven by expanding nutraceutical and cosmetic industries. Brazil and Mexico lead demand, fueled by increasing consumer awareness of skin health and dietary supplements. Local production remains limited, making imports crucial. The region's pharmaceutical sector, while smaller, offers niche opportunities for high-purity applications. Economic stability and regulatory frameworks will significantly impact future growth, with potential for domestic manufacturing to emerge as demand solidifies. Overall, a region poised for moderate, steady expansion, closely tied to consumer packaged goods trends.
The Middle East & Africa L-Pyroglutamic Acid market is nascent but shows potential. Saudi Arabia and the UAE are emerging as key regional players, driven by growing pharmaceutical and cosmetic sectors. South Africa also contributes, particularly in the personal care industry. Local production is limited, with most supply originating from Asia. Increasing awareness of natural ingredients and demand for specialty chemicals are expected to fuel regional growth. Challenges include political instability in some areas and price sensitivity. Investments in R&D and manufacturing infrastructure are crucial for market expansion in this region.
Top Countries Overview
The United States is a key player in the global L-Pyroglutamic Acid market, primarily as a consumer and importer for various applications like pharmaceuticals, cosmetics, and food. Domestic production is limited, driving reliance on international suppliers. Market growth in the US is propelled by expanding demand in these downstream industries.
China dominates global L-Pyroglutamic acid production, driven by demand in pharmaceuticals, cosmetics, and food. The market is expanding with increasing applications. Chinese manufacturers hold a significant competitive advantage due to cost efficiencies and scale, influencing global supply and pricing.
India's global L-Pyroglutamic Acid market presence is evolving. Local production meets some domestic demand, with imports supplementing. Growth is driven by the food, pharmaceutical, and cosmetic industries. Research into novel applications further expands its market potential, indicating a gradual increase in India's global market share in coming years.
Impact of Geopolitical and Macroeconomic Factors
Escalating geopolitical tensions could disrupt supply chains for key raw materials sourced from politically volatile regions, impacting L-Pyroglutamic Acid production costs. Trade protectionism and new tariffs on specialty chemicals would further inflate prices, potentially shifting manufacturing to lower cost countries but hindering innovation investment due to market fragmentation.
Macroeconomically, global inflation pressures and rising interest rates will increase operating expenses for manufacturers, likely passing costs onto consumers or reducing profit margins. Currency fluctuations, particularly a strong US dollar, make imports more expensive for many markets, influencing purchasing power and demand for L-Pyroglutamic Acid derivatives in food, pharmaceutical, and cosmetic applications.
Recent Developments
- March 2025
Ajinomoto Co. announced a strategic initiative to expand its L-Pyroglutamic Acid production capacity in Southeast Asia. This move aims to cater to the growing demand from the personal care and pharmaceutical sectors in the APAC region.
- January 2025
Zhangjiagang Huachang Chemical launched a new high-purity grade of L-Pyroglutamic Acid specifically for the advanced electronics industry. This product offers enhanced thermal stability and reduced impurity levels, meeting stringent industry requirements.
- November 2024
Evonik Industries entered into a partnership with Zhejiang Jianye Chemical to co-develop sustainable production methods for L-Pyroglutamic Acid. This collaboration focuses on reducing the environmental footprint of existing manufacturing processes through bio-catalysis.
- February 2025
Hubei Huitian New Materials completed the acquisition of a smaller, specialized L-Pyroglutamic Acid producer in Eastern China. This acquisition is expected to strengthen Huitian's market share in the domestic cosmetic ingredient sector and expand its product portfolio.
- April 2025
Merck Group unveiled a new research and development strategic initiative focused on exploring novel applications of L-Pyroglutamic Acid in drug delivery systems. The initiative aims to leverage the compound's unique properties for enhanced therapeutic efficacy.
Key Players Analysis
Key players like Ajinomoto Co and Evonik Industries are pivotal in the global L Pyroglutamic Acid market, driving innovation and expanding applications. Zhangjiagang Huachang Chemical and Hubei Huitian New Materials also hold significant positions, contributing to diverse industrial needs. Technologies often involve advanced fermentation and chemical synthesis processes. Strategic initiatives focus on R&D for novel derivatives, optimizing production efficiency, and expanding into new end use sectors like pharmaceuticals and cosmetics. Market growth is primarily driven by increasing demand for natural and bio based ingredients, functional food additives, and intermediates in specialty chemical production. SABIC and Merck Group contribute through their extensive chemical portfolios and global distribution networks.
List of Key Companies:
- Zhangjiagang Huachang Chemical
- Ajinomoto Co
- Evonik Industries
- Hubei Huitian New Materials
- Hubei Zhengjin Xinyuan Chemical
- Tianjin Kermel Chemical
- SABIC
- Loba Chemie
- Zhejiang Jianye Chemical
- Merck Group
- Mitsubishi Gas Chemical Company
- Nantong Huale Chemical
Report Scope and Segmentation
| Report Component | Description |
|---|---|
| Market Size (2025) | USD 0.21 Billion |
| Forecast Value (2035) | USD 0.38 Billion |
| CAGR (2026-2035) | 6.2% |
| Base Year | 2025 |
| Historical Period | 2020-2025 |
| Forecast Period | 2026-2035 |
| Segments Covered |
|
| Regional Analysis |
|
Table of Contents:
List of Figures
List of Tables
Table 1: Global L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Application, 2020-2035
Table 2: Global L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Form, 2020-2035
Table 3: Global L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Grade, 2020-2035
Table 4: Global L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Distribution Channel, 2020-2035
Table 5: Global L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Region, 2020-2035
Table 6: North America L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Application, 2020-2035
Table 7: North America L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Form, 2020-2035
Table 8: North America L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Grade, 2020-2035
Table 9: North America L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Distribution Channel, 2020-2035
Table 10: North America L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Country, 2020-2035
Table 11: Europe L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Application, 2020-2035
Table 12: Europe L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Form, 2020-2035
Table 13: Europe L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Grade, 2020-2035
Table 14: Europe L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Distribution Channel, 2020-2035
Table 15: Europe L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Country/ Sub-region, 2020-2035
Table 16: Asia Pacific L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Application, 2020-2035
Table 17: Asia Pacific L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Form, 2020-2035
Table 18: Asia Pacific L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Grade, 2020-2035
Table 19: Asia Pacific L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Distribution Channel, 2020-2035
Table 20: Asia Pacific L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Country/ Sub-region, 2020-2035
Table 21: Latin America L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Application, 2020-2035
Table 22: Latin America L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Form, 2020-2035
Table 23: Latin America L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Grade, 2020-2035
Table 24: Latin America L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Distribution Channel, 2020-2035
Table 25: Latin America L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Country/ Sub-region, 2020-2035
Table 26: Middle East & Africa L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Application, 2020-2035
Table 27: Middle East & Africa L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Form, 2020-2035
Table 28: Middle East & Africa L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Grade, 2020-2035
Table 29: Middle East & Africa L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Distribution Channel, 2020-2035
Table 30: Middle East & Africa L-Pyroglutamic Acid Market Revenue (USD billion) Forecast, by Country/ Sub-region, 2020-2035