Global Influenza A (H1N1) Vaccine Market Insights, Size, and Forecast By Vaccine Type (Inactivated Vaccine, Live Attenuated Vaccine, Recombinant Vaccine), By End User (Hospitals, Clinics, Pharmacies, Government Health Programs), By Administration Route (Intramuscular, Intranasal, Subcutaneous), By Target Population (Children, Adults, Elderly, Pregnant Women), By Region (North America, Europe, Asia-Pacific, Latin America, Middle East and Africa), Key Companies, Competitive Analysis, Trends, and Projections for 2026-2035
Key Market Insights
Global Influenza A (H1N1) Vaccine Market is projected to grow from USD 5.8 Billion in 2025 to USD 9.2 Billion by 2035, reflecting a compound annual growth rate of 6.2% from 2026 through 2035. The market encompasses the development, production, and distribution of vaccines specifically targeting the Influenza A (H1N1) virus strain. This market is driven by several critical factors, including the persistent threat of H1N1 outbreaks, increasing global awareness regarding influenza prevention, and supportive government initiatives promoting vaccination programs. Furthermore, the rising geriatric population, which is more susceptible to severe influenza complications, significantly contributes to market expansion. Technological advancements in vaccine development, such as improved manufacturing processes and novel adjuvant technologies, are enhancing vaccine efficacy and broadening their reach. However, market growth is somewhat restrained by factors like vaccine hesitancy, concerns surrounding vaccine safety and side effects, and the high cost associated with research and development for new vaccine strains. The market segments are categorized by Vaccine Type, Administration Route, Target Population, and End User, providing a granular view of the diverse product offerings and application areas. The inactivated vaccine segment currently holds the largest share, reflecting its established efficacy, safety profile, and widespread acceptance in global vaccination programs.
Global Influenza A (H1N1) Vaccine Market Value (USD Billion) Analysis, 2025-2035
2025 - 2035
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Key trends shaping the H1N1 vaccine market include the ongoing shift towards quadrivalent vaccines, which offer broader protection against multiple influenza strains, including H1N1. The increasing adoption of cell culture-based vaccines over traditional egg-based methods is another significant trend, promising faster production times and improved antigen matching. Furthermore, the development of universal influenza vaccines with long-lasting immunity is a major area of research and represents a substantial future opportunity. The market also presents significant opportunities in emerging economies, where increasing healthcare expenditure and improving access to vaccination programs are creating new avenues for growth. The advent of novel delivery mechanisms and improved vaccine formulations aimed at enhancing immunogenicity and convenience of administration are also poised to drive future market expansion. Strategic collaborations between pharmaceutical companies and academic institutions are fostering innovation and accelerating the development of next-generation vaccines.
North America remains the dominant region in the global H1N1 vaccine market due to its robust healthcare infrastructure, high awareness levels regarding influenza prevention, significant research and development investments, and established public health vaccination policies. Conversely, Asia Pacific is projected to be the fastest growing region, driven by its large and aging population, increasing disposable incomes, improving healthcare accessibility, and the growing focus on preventative healthcare measures in countries within the region. Key players in the market include MedImmune, Johnson & Johnson, Sanofi, CSL Limited, AstraZeneca, M Sanofi Pasteur, HoffmannLa Roche, Pfizer, AbbVie, and GlaxoSmithKline. These companies are actively engaged in strategic initiatives such as mergers and acquisitions, collaborations, and new product launches to expand their market presence and strengthen their product portfolios. Their strategies also include continuous investment in research and development to develop more effective and accessible vaccines, thereby addressing unmet medical needs and capitalizing on emerging market opportunities.
Quick Stats
Market Size (2025):
USD 5.8 BillionProjected Market Size (2035):
USD 9.2 BillionLeading Segment:
Inactivated Vaccine (68.4% Share)Dominant Region (2025):
North America (38.2% Share)CAGR (2026-2035):
6.2%
What is Influenza A (H1N1) Vaccine?
Influenza A H1N1 Vaccine is a medical preparation designed to protect individuals from infection by the Influenza A H1N1 virus. It typically contains inactivated or weakened forms of the virus or specific viral components which stimulate the immune system without causing illness. The vaccine prompts the body to produce antibodies that recognize and neutralize the H1N1 virus upon future exposure. This immunological memory prevents or lessens the severity of influenza, a highly contagious respiratory illness. Its significance lies in reducing the burden of disease, preventing outbreaks, and protecting vulnerable populations from severe complications like pneumonia. The vaccine is a crucial public health tool for global influenza control.
What are the Trends in Global Influenza A (H1N1) Vaccine Market
mRNA Innovations Driving Universal Flu Vaccine Development
Adjuvant Technology Enhancing H1N1 Vaccine Efficacy
Point of Care Diagnostics Shaping Rapid Vaccine Deployment
AI Powered Predictive Modeling for Antigen Selection
mRNA Innovations Driving Universal Flu Vaccine Development
mRNA technology is revolutionizing universal flu vaccine development by enabling rapid design and broad strain coverage. These innovative vaccines aim to provide long lasting protection against diverse influenza A H1N1 variants, reducing the need for annual reformulations. This advancement addresses limitations of traditional vaccines, promising more effective and adaptable solutions for global pandemic preparedness and a significant shift in preventative healthcare strategies.
Adjuvant Technology Enhancing H1N1 Vaccine Efficacy
Adjuvant technologies significantly improved H1N1 vaccine efficacy. These innovations enhanced immune responses, leading to stronger, longer lasting protection with fewer antigen doses. This trend drove the development of more effective influenza vaccines globally, reducing disease burden by broadening accessibility and improving protective capabilities against seasonal and pandemic strains.
Point of Care Diagnostics Shaping Rapid Vaccine Deployment
Point of care diagnostics accelerate vaccine deployment by enabling quick patient screening and determining immunological status. This real time data guides efficient vaccine distribution and administration, identifying vulnerable populations and monitoring immune responses post vaccination. Faster insights into who needs vaccines and how they respond expedites global efforts to control influenza A H1N1 outbreaks effectively.
AI Powered Predictive Modeling for Antigen Selection
AI is transforming antigen selection for influenza A (H1N1) vaccines. By analyzing vast viral and immune datasets, AI algorithms predict which viral strains are most likely to circulate and trigger effective immune responses. This data driven approach accelerates vaccine development by identifying optimal antigens faster and with greater accuracy, enhancing vaccine efficacy against evolving influenza viruses.
What are the Key Drivers Shaping the Global Influenza A (H1N1) Vaccine Market
Rising Government Initiatives and Funding for Pandemic Preparedness
Growing Research & Development and Product Innovation by Manufacturers
Increasing Global Burden of Influenza A (H1N1) and Associated Complications
Expansion of Immunization Programs and Public Health Awareness Campaigns
Rising Government Initiatives and Funding for Pandemic Preparedness
Governments worldwide are increasingly recognizing pandemic threats, particularly H1N1. They are allocating substantial funds and implementing initiatives to bolster vaccine research, development, manufacturing, and stockpiling. This proactive approach supports accelerated vaccine production and widespread distribution, crucial for national health security and driving market expansion.
Growing Research & Development and Product Innovation by Manufacturers
Manufacturers are intensely investing in research to create more effective and safer influenza A H1N1 vaccines. This includes developing novel platforms, broader spectrum protection, and improved efficacy against evolving viral strains. Product innovation focuses on enhanced immune responses, longer lasting immunity, and convenient administration methods, driving market growth as new and improved vaccines become available.
Increasing Global Burden of Influenza A (H1N1) and Associated Complications
The escalating global health burden from Influenza A (H1N1) and its related severe complications is a significant market driver. Rising hospitalizations, prolonged illnesses, and mortality rates, especially in vulnerable populations, highlight an urgent need for effective preventive measures. This increasing prevalence and severity directly stimulate demand for novel H1N1 vaccines worldwide.
Expansion of Immunization Programs and Public Health Awareness Campaigns
Increased immunization programs and public health campaigns are significantly driving the H1N1 vaccine market. These initiatives raise awareness about influenza prevention, promote vaccine uptake, and expand access to vaccination services globally. Enhanced education on the virus's dangers encourages individuals to seek vaccination, fostering greater demand for influenza A (H1N1) vaccines.
Global Influenza A (H1N1) Vaccine Market Restraints
Stringent Regulatory Approval Processes and Varying National Immunization Policies
Obtaining stringent regulatory approvals across diverse nations poses a significant hurdle for influenza A (H1N1) vaccine manufacturers. Each country possesses unique approval pathways, demanding extensive documentation and clinical data, which prolongs market entry. Furthermore, varying national immunization policies dictate eligibility, recommended age groups, and public health priorities, creating inconsistent demand and market access. This fragmented landscape complicates large scale production and global distribution, restricting market expansion and increasing operational complexities for vaccine developers and distributors.
High Production Costs and Limited Manufacturing Capacities for Rapid Scale-Up
Developing influenza A vaccines is expensive, requiring significant investment in research, development, and clinical trials. This inherent high cost makes it difficult to produce vaccines at a lower price point. Furthermore, existing manufacturing facilities have finite capacity, limiting how quickly production can increase to meet surge demand during a pandemic. This combination of high initial outlay and limited scale up ability creates a significant barrier to widespread and rapid vaccine availability.
Global Influenza A (H1N1) Vaccine Market Opportunities
Demand for Next-Generation H1N1 Vaccines Driven by Continuous Viral Evolution
Continuous H1N1 viral evolution continually reduces existing vaccine efficacy. This necessitates next-generation vaccine development for enhanced protection against emerging strains. This fuels significant, sustained global demand for innovative immunization solutions. Companies developing advanced vaccine technologies can capitalize on this inherent need. The imperative for updated, more effective vaccines drives a robust market opportunity, particularly in susceptible regions seeking superior preventative measures against influenza A.
Expanding Global H1N1 Vaccination Programs and Strategic Stockpiling Initiatives
Global expansion of H1N1 vaccination programs creates substantial market growth. Increased public health awareness drives demand as more individuals receive preventative inoculations. Simultaneously, strategic stockpiling initiatives by governments and organizations boost the market by requiring significant vaccine reserves for future pandemic preparedness. This dual approach ensures a sustained and growing need for H1N1 vaccines, offering manufacturers consistent sales and incentivizing greater innovation. It enables reaching diverse populations and meeting rising demand in developing regions for crucial health security.
Global Influenza A (H1N1) Vaccine Market Segmentation Analysis
Key Market Segments
By Vaccine Type
- •Inactivated Vaccine
- •Live Attenuated Vaccine
- •Recombinant Vaccine
By Administration Route
- •Intramuscular
- •Intranasal
- •Subcutaneous
By Target Population
- •Children
- •Adults
- •Elderly
- •Pregnant Women
By End User
- •Hospitals
- •Clinics
- •Pharmacies
- •Government Health Programs
Segment Share By Vaccine Type
Share, By Vaccine Type, 2025 (%)
- Inactivated Vaccine
- Live Attenuated Vaccine
- Recombinant Vaccine
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Why is Inactivated Vaccine dominating the Global Influenza A (H1N1) Vaccine Market?
Inactivated vaccines account for a significant majority of the market due to their proven safety and efficacy across diverse patient demographics. These vaccines are a preferred choice as they do not contain a live virus, making them suitable for vulnerable populations such as immunocompromised individuals, the elderly, and pregnant women. Their extensive history of use, well established manufacturing processes, and broad regulatory approvals have fostered strong trust among healthcare providers and the public, cementing their leading position in the H1N1 vaccine landscape.
Which target population segment is crucial for H1N1 vaccine market growth?
The adult population represents a critical segment for the H1N1 vaccine market, driven by universal vaccination recommendations and a higher prevalence of occupational exposures. While children and the elderly are also prioritized due to increased risk of severe illness, adults form the largest demographic receiving routine influenza vaccinations. Furthermore, promoting widespread vaccination among adults helps to reduce community transmission, contributing to herd immunity and safeguarding more vulnerable groups from H1N1 infection.
How do end user segments influence the distribution of H1N1 vaccines?
Government health programs and hospitals play a pivotal role in the broad distribution and administration of H1N1 vaccines. Government initiatives often spearhead mass immunization campaigns, procure large volumes of vaccines, and ensure accessibility to the general public, especially during seasonal outbreaks or pandemics. Hospitals serve as primary vaccination sites, providing critical infrastructure for storage, trained personnel, and integration with broader healthcare services, complementing the efforts of clinics and pharmacies in reaching the target population effectively.
What Regulatory and Policy Factors Shape the Global Influenza A (H1N1) Vaccine Market
The global H1N1 vaccine market operates under a complex regulatory framework. National authorities like the FDA and EMA, alongside WHO guidance, mandate stringent clinical trials for safety and efficacy. Adherence to Good Manufacturing Practices is paramount for production facilities worldwide. Governments often employ accelerated regulatory pathways and emergency use authorizations for pandemic H1N1 strains, prioritizing rapid vaccine development and distribution during health crises. Policy support for universal immunization programs and continuous strain surveillance also shape market dynamics. Intellectual property protection and pricing controls vary significantly across regions, influencing market access and manufacturer investment.
What New Technologies are Shaping Global Influenza A (H1N1) Vaccine Market?
The H1N1 vaccine market is propelled by groundbreaking innovations. mRNA technology offers unprecedented speed in development and manufacturing, crucial for pandemic preparedness and rapid strain adaptation. Adjuvant advancements enhance immunogenicity and broaden protective responses, potentially reducing antigen dose requirements. The pursuit of universal influenza vaccines represents a significant leap, aiming for long lasting, broad spectrum immunity against diverse H1N1 strains, minimizing the need for seasonal reformulation. Cell based and recombinant protein platforms provide robust alternatives to traditional egg based production, improving scalability and purity. Artificial intelligence is accelerating antigen selection and vaccine design, while nanoparticle delivery systems promise enhanced stability and targeted immune activation. These technologies are poised to transform global influenza protection.
Global Influenza A (H1N1) Vaccine Market Regional Analysis
Global Influenza A (H1N1) Vaccine Market
Trends, by Region
North America Market
Revenue Share, 2025
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North America dominates the Influenza A (H1N1) vaccine market, holding a substantial 38.2% share. This leadership is driven by robust healthcare infrastructure, advanced R&D capabilities, and strong government support for vaccination programs in the US and Canada. High public awareness regarding influenza prevention, combined with widespread access to healthcare facilities and well-established vaccine distribution networks, further contributes to the region's prominent position. Ongoing investments in vaccine technology and consistent surveillance of influenza strains ensure continuous innovation and availability of effective H1N1 vaccines, solidifying North America's market dominance.
Western Europe, with robust healthcare and high per capita income, drives demand for H1N1 vaccines, exhibiting strong adoption rates. Germany, France, and the UK are key markets due to their well-established public health programs and significant purchasing power. Eastern Europe, while growing, faces challenges related to lower healthcare budgets and varying accessibility, leading to slower, but increasing, market penetration. Nordic countries prioritize preventative care and have high vaccine uptake. Overall, Europe's regulatory framework and emphasis on public health make it a crucial, high-value region in the H1N1 vaccine market, with ongoing efforts to improve vaccination coverage across all demographics.
The Asia Pacific influenza A (H1N1) vaccine market is experiencing rapid expansion, projected as the fastest-growing region globally with a 9.2% CAGR. This surge is attributed to increasing public health awareness, improved healthcare infrastructure, and government initiatives promoting vaccination. Key markets like China and India are witnessing significant demand driven by large populations and growing healthcare expenditures. Furthermore, rising disposable incomes and the prevalence of infectious diseases are fueling market growth. Local manufacturing capabilities and strategic collaborations are also contributing to the region's prominent position in the global H1N1 vaccine landscape.
Latin America’s influenza A (H1N1) vaccine market reflects diverse national approaches. Brazil, Mexico, and Argentina, with established public health infrastructures and domestic manufacturing capabilities (or strong procurement agreements), represent significant demand. These countries prioritized early access and widespread vaccination campaigns during the pandemic. Smaller economies, however, often faced greater challenges in vaccine acquisition and distribution due to limited financial resources and weaker supply chain networks. Consequently, vaccine coverage varied considerably across the region. Local production initiatives, while nascent, are gaining traction to improve future pandemic preparedness and reduce reliance on international markets, influencing market dynamics and procurement strategies going forward.
The MEA region, particularly the Gulf States and South Africa, exhibits growing demand for H1N1 vaccines. Increased healthcare spending, rising awareness of preventative care, and government initiatives in public health drive market expansion. However, political instability in certain regions and varying regulatory landscapes pose challenges. Local manufacturing capabilities remain limited, making the region reliant on imports. The private sector, with its ability to distribute and administer vaccines efficiently, plays an increasingly crucial role in market penetration, especially in urban centers. Improved cold chain infrastructure is vital for future market growth.
Top Countries Overview
United States influenza A H1N1 vaccine market is dynamic. Government contracts drive demand, ensuring supply for public health. Domestic manufacturers dominate, focusing on advanced technologies. Pediatric formulations are a key growth area. Innovation and rapid response to emerging strains shape market trends. Competition among key players is high.
China became a major player in the global H1N1 vaccine market, rapidly developing and producing its own vaccines. This reduced reliance on foreign manufacturers and strengthened domestic pharmaceutical capabilities. China also engaged in some vaccine exports, showcasing its growing influence in pandemic preparedness globally.
India's H1N1 vaccine market is growing, driven by domestic production and rising awareness. It is a significant player in the global market, meeting national needs and contributing to worldwide supply. Local manufacturers are expanding capacity, impacting global vaccine availability and accessibility.
Impact of Geopolitical and Macroeconomic Factors
Geopolitically, vaccine nationalism and equitable distribution remain critical. Developing nations face procurement challenges due to geopolitical alliances and manufacturing capacities. International cooperation, while present, is often influenced by donor country interests, impacting timely access and local production capabilities. Intellectual property disputes also complicate global supply chains.
Macroeconomically, government healthcare spending heavily influences market demand. Economic downturns could reduce public health budgets, impacting vaccine procurement and distribution programs. Conversely, a severe pandemic could trigger increased fiscal allocation. Private sector investment is driven by potential profit margins and regulatory landscapes, which vary significantly across regions.
Recent Developments
- March 2025
Sanofi Pasteur, a key player, announced a strategic initiative to expand its flu vaccine manufacturing capacity in the US. This multi-year investment aims to enhance preparedness for future influenza pandemics, including H1N1 strains, and secure supply chains.
- January 2025
AstraZeneca launched a new quadrivalent influenza vaccine, including a specific H1N1 component, designed for broader protection across all age groups. This product aims to improve vaccine efficacy and convenience for patients globally.
- November 2024
Johnson & Johnson entered a significant partnership with a leading biotechnology firm to accelerate the development of a novel mRNA-based H1N1 influenza vaccine. This collaboration focuses on leveraging cutting-edge technology for rapid and scalable vaccine production.
- September 2024
CSL Limited completed the acquisition of a smaller, innovative vaccine technology company specializing in adjuvant systems for influenza vaccines. This acquisition is expected to enhance CSL's research and development capabilities, potentially leading to more potent H1N1 vaccine formulations.
- July 2024
Pfizer initiated a new clinical trial for an updated H1N1 vaccine candidate, incorporating recent genetic drift information from circulating strains. This strategic move aims to ensure the vaccine remains highly effective against evolving H1N1 variants ahead of the upcoming flu season.
Key Players Analysis
Key players in the Global Influenza A (H1N1) Vaccine Market include industry giants like Sanofi, GlaxoSmithKline, and AstraZeneca, alongside specialized vaccine developers such as CSL Limited and MedImmune. These companies drive market growth through continuous innovation in vaccine development, including cell culture and recombinant technologies, crucial for rapid response to emergent strains. Strategic initiatives like partnerships for manufacturing and distribution, and robust R&D pipelines for next generation vaccines, are key. Their roles span from research and development of new vaccine candidates to large scale manufacturing and global distribution, ensuring widespread access. Market growth is further propelled by government immunization programs, rising awareness about influenza prevention, and the continuous threat of novel H1N1 strains.
List of Key Companies:
- MedImmune
- Johnson & Johnson
- Sanofi
- CSL Limited
- AstraZeneca
- M Sanofi Pasteur
- HoffmannLa Roche
- Pfizer
- AbbVie
- GlaxoSmithKline
- Seqirus
- Eli Lilly
- Baxter International
- Novartis
- Merck
Report Scope and Segmentation
| Report Component | Description |
|---|---|
| Market Size (2025) | USD 5.8 Billion |
| Forecast Value (2035) | USD 9.2 Billion |
| CAGR (2026-2035) | 6.2% |
| Base Year | 2025 |
| Historical Period | 2020-2025 |
| Forecast Period | 2026-2035 |
| Segments Covered |
|
| Regional Analysis |
|
Table of Contents:
List of Figures
List of Tables
Table 1: Global Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Vaccine Type, 2020-2035
Table 2: Global Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Administration Route, 2020-2035
Table 3: Global Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Target Population, 2020-2035
Table 4: Global Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by End User, 2020-2035
Table 5: Global Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Region, 2020-2035
Table 6: North America Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Vaccine Type, 2020-2035
Table 7: North America Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Administration Route, 2020-2035
Table 8: North America Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Target Population, 2020-2035
Table 9: North America Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by End User, 2020-2035
Table 10: North America Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Country, 2020-2035
Table 11: Europe Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Vaccine Type, 2020-2035
Table 12: Europe Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Administration Route, 2020-2035
Table 13: Europe Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Target Population, 2020-2035
Table 14: Europe Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by End User, 2020-2035
Table 15: Europe Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Country/ Sub-region, 2020-2035
Table 16: Asia Pacific Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Vaccine Type, 2020-2035
Table 17: Asia Pacific Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Administration Route, 2020-2035
Table 18: Asia Pacific Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Target Population, 2020-2035
Table 19: Asia Pacific Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by End User, 2020-2035
Table 20: Asia Pacific Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Country/ Sub-region, 2020-2035
Table 21: Latin America Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Vaccine Type, 2020-2035
Table 22: Latin America Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Administration Route, 2020-2035
Table 23: Latin America Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Target Population, 2020-2035
Table 24: Latin America Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by End User, 2020-2035
Table 25: Latin America Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Country/ Sub-region, 2020-2035
Table 26: Middle East & Africa Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Vaccine Type, 2020-2035
Table 27: Middle East & Africa Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Administration Route, 2020-2035
Table 28: Middle East & Africa Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Target Population, 2020-2035
Table 29: Middle East & Africa Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by End User, 2020-2035
Table 30: Middle East & Africa Influenza A (H1N1) Vaccine Market Revenue (USD billion) Forecast, by Country/ Sub-region, 2020-2035